Metabolism and functional effects of sphingolipids in blood cells
نویسندگان
چکیده
منابع مشابه
Metabolism and signalling effects of sphingolipids
Sphingomyelin metabolism generates anticancer signals such as ceramide and sphingosine that may inhibit cell proliferation, and induce differentiation and apoptosis. Changes of sphingomyelin metabolism are found to be associated with tumorigenesis in various tissues and a particular link between sphingomyelin metabolism and colon cancer has been indicated. The effects of several anticancer drug...
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Sphingolipids (SLs) are essential constituents of eukaryotic cells. Besides playing structural roles in cellular membranes, some metabolites, including ceramide, sphingosine, and sphingosine-1-phosphate, have drawn attention as bioactive signaling molecules involved in the regulation of cell growth, differentiation, senescence, and apoptosis. Understanding the many cell regulatory functions of ...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1999
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.1999.01697.x